Bruce Jenkins left his Mosgiel home for work this morning at 9.30am, but did not arrive.
Mr Jenkins has been travelling in a silver Holden Astra hatchback, registration number YJ4205.
Police are wanting to hear from anyone who knows where he is or has seen his vehicle.
The public are asked to not approach him or his vehicle; rather they should contact 111 immediately.
Alternatively, information can be provided anonymously via the organisation Crimestoppers on 0800 555 111.