The pioneering researcher who spent decades researching honey
and other natural antibiotics, biochemist Peter Molan, has
developed his own "gold standard" for measuring biological
activity in manuka honey.
Professor Molan, from Waikato University's honey research
unit, spent years providing the scientific underpinnings for
New Zealand's valuable export trade in anti-bacterial manuka
honey.
Manuka honey has proven effective against major
wound-infecting bacteria and the bacteria which causes
stomach ulcers.
But late last year the researcher threw up his hands over
industry infighting about how biologically active manuka
honey should be measured and ranked.
Prof Molan told honey companies in a personal email that he
would no longer have anything to do with the Active Manuka
Honey Association (AMHA), which had 48 members, with 32
licensed to use its trademarked unique manuka factor (UMF)
ratings.
The AMHA was created only after Prof Molan was asked by
Government trade officials to help set up an industry group
for producers of active manuka honey.
And the UMF testing on which it relies uses a method
described by Dr Molan and other honey researchers at Waikato
University in 1991 to underpin domestic and export manuka
honey markets worth more than $100 million a year.
UMF ratings are based on measurement of the antibacterial
activity of samples of honey to indicate how well it fights a
wide range of very resistant bacteria.
Separately, the association has been caught up with another
company, Manuka Health NZ Ltd, which acquired research from
overseas to argue objective measurement of the active
ingredient methylglyoxal might be the best way to measure
anti-bacterial strength.
Manuka Health has said the results of UMF testing can be
changed by heating honey, and that differences of up to $2000
in payment for a 300kg drum of honey had led to conflict
between beekeepers and honey producers.
Dr Molan - who has said methylglyoxal is not a reliable
indicator of anti-microbial activity - has instead produced
new research into the nature of the antibacterial substances
and why testing of some manuka honey indicated only partial
inhibition of bacteria.
Scientists are now able to reliably measure activity in
manuka honey in a way which will show the true full
antibacterial activity, and the intellectual property
involved is controlled by Waikato University.
Prof Molan said care was needed in marketing anti-microbial
manuka honey.
"Not all manuka honeys have true medicinal bioactivity beyond
the range that's normal of all honeys, and the industry is
exposed if it does not make the distinction clear," he said.
Several manuka honeys labelled as "active" in combination
with a number had little or none of the non-peroxide activity
that was the key to its distinctive antibacterial qualities.
Active manuka honey can sell for about $65 for a 250gm jar in
countries such as Britain.
Now Waikato University is providing manuka honey marketers
with its new international standard to allowing trademarking
of authenticated medicinal honeys.
A commercial manager for the university, Fraser Smith, said
the name Molan Gold Standard was linked with the honesty and
integrity of Prof Molan.
"Professor Molan has agreed to put his name to honeys that
meet his own ethical and scientific standards," he said.
The antibacterial activity of manuka honey could be use
against the antibiotic-resistant bacteria now becoming a
major problem in hospital "superbugs" .
It was effective against subcutaneous infections, such as
acne and sinusitis, and methods had also been developed for
measuring antioxidant content relevant to digestive health
and anti-inflammatory properties.
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