Rice, at a White House briefing, responded to a report that President Barack Obama had written a letter to Iran's Supreme Leader Ayatollah Ali Khamenei about Islamic State by saying, "We are in no way engaged in any coordination - military coordination - with Iran on countering ISIL."
Rice also said US concerns about cybersecurity would be high on the agenda when President Barack Obama meets Chinese officials in Beijing next week.
Rice said there no plans for a formal meeting between Obama and Russian President Vladimir Putin at a G20 summit but that there might be opportunity for informal discussions.