Cairns has pleaded not guilty to a perjury charge stemming from a 2012 libel trial in Britain over alleged match-fixing.
He will appear in Southwark Crown Court on Monday (local time) in front of Justice Nigel Sweeney at a hearing scheduled to last four weeks.
Cairns won STG90,000 in damages in 2012 when he sued Indian Premier League founder Lalit Modi over a tweet that accused the New Zealander of match-fixing.
The crown alleges Cairns made a statement during that trial that he knew to be false when he declared he'd "never, ever cheated at cricket".
The trial has been delayed to allow testimony from key witnesses who are available only during down time in the international cricket calendar.
Former New Zealand cricketers Shane Bond and Andre Adams are among those scheduled to testify, as well as current skipper Brendon McCullum.
