They are the only two changes to the side, which will be looking for its first win in Perth since 2007.
Highlanders: Ben Smith (co-captain), Waisake Naholo, Malakai Fekitoa, Shaun Treeby, Patrick Osborne, Lima Sopoaga, Aaron Smith, Nasi Manu (co-captain), John Hardie, Gareth Evans, Mark Reddish, Alex Ainley, Josh Hohneck, Liam Coltman, Kane
Hames. Reserves: Ash Dixon, Daniel Lienert-Brown, Ross Geldenhuys, Tom Franklin, Dan Pryor, Fumiaki Tanaka, Richard Buckman, Marty Banks.