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Contractors demolish the Barningham Building behind the University of Otago School of Dentistry complex on Thursday.
The two-storey building was once part of the larger Victoria Foundry of Barningham and Co, and was also the previous home of the university's Dunedin Multidisciplinary Health and Development Research Unit.
The unit is now located in part of the Logan Park Annexe, near the University Oval.
The unit's Dunedin Study has followed the lives of more than 1000 babies born between April 1, 1972 and March 31, 1973 at the former Queen Mary Maternity Hospital.
The demolition work is part of an extensive redevelopment which will result in a new clinical building being added to the School of Dentistry complex.