Retail development manager Cat Callanan said the celebration on September 1 marked the 10 years since the shop opened in Mosgiel.
During the decade, the shop had several shop managers, with each adding their own signature to the shop.
The biggest change was in 2017 when Tina Tunster took the shop from its former small premises to the current premise just three doors down on Gordon Rd.
This move resulted in a doubling of the shop's turnover.
The celebration also marked the shop's two-year anniversary in the new site.
Ms Tunster has now moved on and new shop manager Anke Hoggett-Schnebeck arrived last month, just in time to arrange the celebrations.
The Mosgiel Hospice Shop was a key part of the hospice fundraising efforts, generating $170,000 for the hospice in the last financial year.
At the celebrations, four volunteers - Daphne Parsons, Mary Tisdall, Elisabeth Govaerts and Sheryl Fuller - who had helped out at the shop since day one were commemorated.
The shop has been a real jewel in the hospice shop network.
"The Mosgiel community has really wrapped around our hospice shop with incredible support as volunteers, donors and shoppers.
"`It's a real tribute to this community, raising such significant sums for hospice service in this region ...
"Unfortunately the fundraising need never ceases and we are always looking for new volunteers to help us in the shop...''
- Staff reporter