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A police spokeswoman said the collision occurred on Ruakura Rd in the suburb of Hamilton East about 12.40pm today.
The southbound lanes were initially closed by police but reopened about 1.30pm.
At the scene, a woman driving a red car could be seen speaking with police at the exit of the Hilda Ross rest home, while a lime scooter was parked nearby.
A second lime scooter was also parked at the scene.
Police at the crash said they couldn't comment about what happened, but a St John spokeswoman confirmed a person had been taken to Waikato Hospital with serious injuries.