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The Afghan girl, said to be as young as 8, was held in Helmand province as she tried to carry out an attack on border police, BBC reports.
The girl was thought to be the sister of a prominent Taliban commander, who encouraged to carry out the attack.
Either she could not operate the button to detonate the suicide vest, or she was arrested before she could carry out the attack, an interior ministry spokesman said.
The girl has now been transferred to the provincial capital of Lashkar Gah.