Emergency services were advised of the crash on the Kurow-Duntroon Road (State Highway 83) about 12.40pm today, a spokeswoman said.
A person died at the scene. No other vehicles were involved.
The crash had closed SH83, east of the intersection of Eastern Rd, Waka Kotahi/ NZ Transport Agency advised.
However, by 3.40pm the road had reopened to one lane, with stop-go traffic management in place.
An ODT reporter at the scene said there was debris scattered over the Alps 2 Ocean Cycle Trail and a roadside paddock from the crash.
Motorists were advised to expect delays.