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Emergency services are at the scene of a serious crash between a car and a motorcycle in Waimate.
A St John spokeswoman said two ambulances responded to the crash and three patients with minor to moderate injuries were being treated at the scene.
One person in a moderate condition was being transported to Timaru Hospital by ambulance.
Police were called to the scene, between Oxford and Regent Sts, around 6.15pm.
The road is closed and the Serious Crash Unit has been advised.
Motorists are advised to avoid the area.