A police spokeswoman said the accident happened near Moneymore Rd, just south of the State Highway 8 intersection about 12.30pm.
A car travelling north and a truck travelling south collided, blocking both lanes of SH1.A van following the northbound car veered off the road into a ditch, ending up on its side.
A St John spokesman said two ambulances and a helicopter were sent to the scene.
They also treated two people for minor injuries at the scene.
The highway was closed yesterday afternoon and diversions were in place for light traffic at Adams Flat Rd and Creighton Rd. Heavy trucks were periodically being allowed through.
The highway reopened again at 6.20pm yesterday.The Serious Crash Unit would investigate the crash, police said.
- Kayla Hodge