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Emergency services were called to the crash at the intersection of Pages and Breezes Rds in Aranui about 8.20am on Monday.
A police spokeswoman said it appeared two cars collided at the intersection.
A St John spokesman said three people were taken to Christchurch Hospital.
He said one person was seriously injured, one was moderately injured and another had minor injuries.
No-one was trapped in the vehicles after the crash and the intersection was reopened about 9.30am.