Click photo to enlarge
AgResearch Invermay senior animal genomics scientist John
McEwan says new SNP Chip technology will revolutionise the
sheep industry to a similar degree as computers. Photo by
Neal Wallace.
A new genetic tool that could be as revolutionary for
sheep breeding as computer technology has been, should be
available to farmers from early next year.
SNP Chips was the result of genetic sequencing of the sheep
genome and allowed researchers to understand the effects of
small genes rather than just the large genes currently
possible.
"It allows you to get better predictions of what the actual
worth of an animal is," AgResearch Invermay senior animal
genomics scientist John McEwan said.
Cumulatively, small genes could add up to 50% to 95% of
genetic variation between animals, he said.
Mr McEwan said research on the technology began 20 years ago.
It could take another 10 before it was fully adopted by the
sheep industry.
In the dairy industry, the two large artificial insemination
companies - LIC and CRV Ambreed New Zealand - had already
adopted SNP Chips, but Mr McEwan said sheep farmers in
general wanted to see how others adapted it.
The United States dairy industry provided evidence of how the
technology could be used.
Historically, each of the top 40 bulls used in artificial
insemination programmes would have be rated following testing
of 80 to 100 daughters, by which stage the average age of
each sire was five years.
Since using SNP Chip technology, just three of the top 40
sires have progeny in milk, with the others ranked on DNA and
parental information.
"That allows generations to be shortened, more accurate
breeding values and greater genetic progress," he said.
Similar progress could be made for the sheep industry, he
said, and three SNP Chip products were likely.
The first would be used on rams to more accurately predict
the performance of progeny for traits such as number of lambs
born.
The second would be used for the top tier of stud rams to
selecting those from which to breed, based on traits such as
meat yield or other desirable attributes.
The third expected test - "parentage-plus" - would record the
birth dam and sire, while adding other tests such as for the
Inverdale gene, the MyoMax DNA test to identify leaner and
meatier carcasses or a test for facial eczema resistance.
But to be really useful and accurate in sheep, the SNP Chip
tests needed to be continually calibrated and updated.
The New Zealand SNP Chip work on sheep was funded by Ovita, a
joint venture between Meat and Wool New Zealand and
AgResearch.
The consortium was 18 months into its second five-year
contract and Mr McEwan said it hoped to embark on two
research programmes.
One would involve identifying animals which had superior
performance while requiring less feed.
The other, in conjunction with the Pastoral Greenhouse Gas
Research Consortium, would look at the breeding of animals
which released less methane.
"We're hopeful we can do this, particularly the methane one.
We're not on a dead-cert, but it maybe possible to breed an
animal which releases less methane - but whether it is
economically viable is another story."
In the future, the SNP Chip would be viewed as comparable to
the contribution computers had made since the 1980s and which
underpinned Sheep Improvement Ltd, LIC and Blup (best linear
unbiased prediction) technology, he said.
"People will look back in 10, 15 or 20 years and say there
was pre-SNP Chip and post-SNP Chip; it's that big a thing,"
Mr McEwan said.
