Senior Sergeant Anthony Bond, of Dunedin, said police responded to an alarm activation at Vapourium, in London St, at 2.55am yesterday.
Two males had smashed into the building an stolen number vape products.
It was the second break-in at Vapourium in less than a month, with the store targeted on October 31.
Retail manager Ziggy Wyllie said when she arrived at work and saw glass all over the floor.
"It’s happened again — we’ve been targeted again, which is unfortunate.
"I guess sadly half-expecting it but also not fun to deal with in general."
She said the same window as the first break-in had been smashed and vapes were scattered all over the ground like "a minefield", she said.
Ms Wylie estimated about 30 disposable vapes were stolen, most of them from a display stand.
With single-use disposable vapes becoming illegal next month, she suspected people were getting impatient.
"They’re stocking up in a way we don’t prefer them to stock up in."
The break-in was part of a crime spree involving a Nissan Tiida and Toyota Corolla, which Snr Sgt Bond said were reportedly seen in the vape store’s vicinity.
The night of mayhem started when police were called to Glendevon Pl, in Vauxhall, at 2am yesterday, where they found a stolen vehicle which had been missing since Sunday night.
As officers waited for a tow truck to arrive, Snr Sgt Bond said a stolen Nissan Tiida pulled up to the property with two people inside.
One of the occupants got out of the Tiida and approached the other vehicle but retreated to the car after noticing police at the scene.
Police attempted to block the Tiida from fleeing but it struck the police car, briefly immobilising it, Snr Sgt Bond said
As police searched the area, a Toyota Corolla was spotted travelling with the same Nissan Tiida.
Police attempted to stop the Corolla, as it had appeared to be racing with the Tiida, but it failed to stop and accelerated along Prince Albert Rd.
Police lost sight of it as it turned on to Bay View Rd on to Andersons Bay Rd where the Corolla began driving on the wrong side of the road.
The Corolla was driving dangerously so police abandoned the pursuit.
Police resumed their search and found the Nissan Tiida again, this time on Larnach Rd.
Members of the public reported it fled on to Marne St then on to Musselburgh Rise travelling at high speeds, Snr Sgt Bond said.
Yesterday, police made inquiries into the Corolla which was believed to be stolen, as it was registered to a company.
The Nissan Tiida is believed to have been stolen from Coast Rd and had still not been recovered, he said.
