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A Fire and Emergency NZ spokesman said the Omakau Volunteer Fire Brigade was called to Poolburn-Moa Creek Rd at 10.30am.
Police were also called and an officer at the scene confirmed to the Otago Daily Times late this morning there had been a fatality, but had no more details.
In an update this afternoon police said the "serious crash involving a motorcycle" was thought to have occurred overnight and one person was found dead at the scene.
The Serious Crash Unit has carried out an examination, and inquiries were continuing.