The Blue and Golds will parade a new locking combination, a club stalwart at flanker and some real speed and trickery on the outsides.
Auckland on the other hand, has stacked its side with Super Rugby players and has six players starting the game who were picked in the All Black named last Sunday.
Otago coach Tom Donnelly has named his first side of the Mitre 10 Cup season and is expecting a big battle from the Auckland side.
Lock Will Tucker has come down from Canterbury and will lock the scrum with Josh Hill, forming a young second-row combination.
Hill has played just seven games for Otago, started just two matches, while Tucker has had just the four outings for Canterbury.
Hill has looked the goods at this level, but the duo will be up against some experienced and quality Auckland locks in Scott Scrafton and Highlanders second rower Jack Whetton.
Irish lock Jack Regan has been named in the reserves and will also make his Otago debut should be get on.
Charles Elton, who played his 100th game for Harbour earlier this season, will make his Otago debut at this level, playing on the blindside flank.
He was the North Otago player of the year last season, helping North Otago to win the Heartland Championship and has been a standout for his Harbour club side in recent years.
But this is a real test for Elton, who will have to stand tall against what appears to be a strong and powerful Auckland side.
Veteran Josh Hohneck will start the game at prop, his first game at this level in New Zealand since the end of 2016.
Josh Ioane comes right back into the starting side at first five-eighth while Aleki Morris-Lome is outside him. Morris-Lome had been out for a couple of months with a finger injury but impressed for Harbour in his return to the field last Saturday.
Josh Timu will start at centre, having played in that position only once previously — against Northland in 2017. He will have the big task of marking All Black Rieko Ioane.
Speedsters Vilimoni Koroi and Jona Nareki are on the wing but will have their hands full taking on new All Black Caleb Clarke and AJ Lam.
Otago winger Freedom Vahaakolo will come off the bench and will make his first-class debut should he get off the field.
He should know the opposition, having played club rugby in Auckland over the past couple of years.
Otago will be going for a hat-trick of wins over Auckland after picking up victories in 2017 and 2018. The two sides did not play each other last year.
The match is for the Lin Colling Trophy which is held by Otago.
Otago v Auckland
FB Stadium, tomorrow, 4.35pm
Otago: Michael Collins (captain), Vilimoni Koroi, Josh Timu, Aleki Morris-Lome, Jona Nareki, Josh Ioane, Kayne Hammington, Dylan Nel, Slade McDowall, Charles Elton, Will Tucker, Josh Hill, Josh Hohneck, Liam Coltman, Jonah Aoina. Reserves: Ricky Jackson, George Bower, Hisa Sasagi, Jack Regan, Nasi Manu, James Arscott, Sio Tomkinson, Freedom Vahaakolo.
Auckland: Jordan Trainor, AJ Lam, Rieko Ioane, TJ Faiane (captain), Caleb Clarke, Harry Plummer, Jonathan Ruru, Hoskins Sotutu, Adrian Choat, Akira Ioane, Jack Whetton, Scott Scrafton, Ofa Tu’ungafasi, Leni Apisai, Alex Hodgman. Reserves: Mike Sosene-Feagai, Jarred Adams, Angus Ta’avao, Liam Hallam-Eames, Blake Gibson, Danny Tusitala, Simon Hickey, Tumua Manu.