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The crash also left the 18-year-old driver with serious injuries.
Waitaki Boys' High School rector Darryl Paterson confirmed to the Otago Daily Times one of the people killed in the crash was a year 12 pupil that had recently left the school.
The driver of the vehicle was also a former pupil, he said.
The single-vehicle crash occurred at the intersection of T Y Duncan Rd and Shortland Rd, Oamaru North about 11pm.
Fire crews were called to T Y Duncan Rd about that time and found a car alight. Two bodies were discovered inside.
Detective Sergeant Hannah Booth, of Oamaru, said the cause of the crash was being investigated.
Det Sgt Booth also confirmed to the Otago Daily Times the two people killed in the crash were from Oamaru.
“It’s too early to tell the cause of the crash at this stage.”
She said the 18-year-old driver was in Dunedin Hospital in a serious but stable condition.
It was expected further details about the two people killed would be made available later today.
Cordons were in place at TY Duncan Rd and Shortland Rd earlier today but have since been removed.
TY Duncan Rd is a rural road off State Highway 1, between the highway and the coast.
Two fire crews were involved in putting out the blaze.
The vehicle has been removed from the scene and the road has been reopened.