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Four men have been shot dead in three days across Melbourne but police have ruled out links between the crimes.
In the latest shooting two men, aged in their 30s, were killed just streets apart in Meadow Heights about 10.15pm on Monday.
"None of the shootings are connected," Crime Command Acting Assistant Commissioner Michael Frewen told reporters on Tuesday.
"But all three shootings do share some degrees of commonality."
In all cases the parties were known to each other, there was a planned contact or meeting arranged and each of those meetings led to a "fatal escalation", Mr Frewen said.
A man was shot dead outside a boxing tournament in Kensington and two others were seriously injured on Friday. Brunswick brothers Abdullah El Nasher, 27, and Ali El Nasher, 28 as well as Pascoe Vale man Mikhael Myko, 25, are wanted for questioning over the fatal attack.
In the second fatal shooting, a man in his 50s was found dead with gunshot wounds in a crashed car on Sunday night, at Dandenong in Melbourne's southeast.
But while Mr Frewen said the shootings were not linked to each other, police hadn't ruled out connections to gang or underworld activity.
"I'm not ruling anything out at this point in time," he said.
Officers from armed crime, the homicide squad and organised crime were working on the shooting cases and police were aware of the potential for revenge attacks.
"Our gangs division and organised crime division are actively working on intervention activities ... so there is no escalation or reprisal activities," Mr Frewen said.
Victoria Premier Daniel Andrews said the shootings were disturbing but his government had passed more laws to improve police powers.
"It's important that we stay the course and support Victoria Police as they get to the bottom of exactly what's happened and crack down on that culture," he told reporters.