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They are curious to find out the history behind the cheque, which still has its stamp attached and was made out to Mawhinney and Geddes.
The cheque, for 31 18s, was found during the installation of insulation in Keeling House, alongside a 1968 newspaper complete with an editorial on student behaviour and half a New Zealand map.
Keeling House sits at the rear of Studholme College, on Clyde St, and is one of eight houses aligned to the college.
Its age is not known.
Head of College Ziggy Lesa said he would like to find out about the history of the cheque, who the people were and what happened to them.
If anyone knew anything about the parties on the cheque he would be keen to hear from them, he said.
After that a decision would be made on the cheque's future.
College maintenance supervisor Brian Hamilton said the cheque was in exceptional condition and he hoped someone affiliated with Mawhinney and Geddes would come forward.