Chairman Martin Paris said he was expecting from 120 to 150 people to attend the celebrations which will start on Friday evening with an informal get-together and an auction night.
Highlanders coach and former Harbour player Tony Brown has been drafted in as a guest speaker. Among the items up for auction is a weekend in Queenstown driving around in a Mustang.
There are also 15 commemorative Harbour jerseys which have been especially designed for the jubilee year. They have also been signed by the Highlander who typically plays in that jersey number.
On Saturday there will be a full day of rugby at Watson Park. The juniors play in the morning and the premier side takes on Green Island in the afternoon.
The club is hoping to shift its senior grade team to the venue so it can play a curtain-raiser for the premier game.
Following the rugby there will be an evening function and buffet meal. The Highlanders match against the Waratahs will also be screened live and a band will take over the entertainment duties following the Super Rugby fixture.
On Sunday there will be a low-key farewell.
Former Port Chalmers player Gary Pringle is making the longest trip. He is travelling from Perth to attend the event.
The Harbour Rugby Football Club was formed in 1992 when the Port Chalmers and Ravensbourne clubs merged.
Both those clubs were more than 100 years old.