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The graffiti reads ''MACK TOGO'' and Roger Knauf, of Graffiti Doctor, said the tag was characteristic of various pieces of graffiti around Dunedin.
''That particular person has been responsible for a lot of height work around town,'' Mr Knauf said.
Because of its size, the best way to remove the graffiti would be a ''complete paint-out'', he said.
When contacted by the Otago Daily Times, the owner of the building did not want to comment.