The jury found Weinstein guilty of rape, forcible oral copulation and sexual penetration by foreign object involving one woman, but acquitted him of charges relating to a second alleged victim.
The jury could not reach a verdict on two allegations, including rape, by Jennifer Siebel Newsom, the wife of California's Democratic Governor Gavin Newsom, and did not reach a verdict on charges relating to one other women.
Weinstein, 70, already is serving a 23-year prison sentence after being convicted of sexual misconduct in New York.
In Los Angeles, Weinstein faced seven counts of rape and sexual assault from four women for encounters between 2004 and 2013.
During five weeks of testimony in Los Angeles Superior Court, accusers including documentary filmmaker Siebel Newsom said Weinstein lured them to what they believed were business meetings.
Superior Court Judge Lisa Lench declared a mistrial on the counts where the jury could not reach a verdict, including the allegations made by Siebel Newsom.
The women had alleged during often-graphic testimony that the powerful producer of "Pulp Fiction" and "Shakespeare in Love" masturbated in front of them and groped or raped them.
Siebel Newsom and three other women offered testimony that provided the basis for the two counts of rape and five counts of sexual assault that Weinstein faced.
Four additional women offered similar stories to buttress the prosecution's arguments that Weinstein routinely abused his position as a Hollywood power player to prey on women.
They said he promised help with securing an audition or a book deal, and then arranged meetings where staff disappeared and left them alone with him.
Weinstein had said all of his sexual encounters were consensual and had pleaded not guilty.
Defense attorneys argued that the women willingly had sex with Weinstein because they believed he would help their careers, part of what they said was a widespread "casting couch" culture in the film industry. In two of the cases, they said the sexual contact was fabricated.
They also highlighted that some of the accusers, including Siebel Newsom, kept in contact with Weinstein, which they argued did not make sense if he had attacked them.
Siebel Newsom attended a pre-Oscars party hosted by Weinstein with her husband, and sent Weinstein dozens of friendly emails over the years.
Weinstein was convicted of sexual misconduct in New York in February 2020. He was extradited from New York to a Los Angeles prison in July 2021.
In New York, Weinstein is appealing his conviction and prison sentence.
Allegations against Weinstein helped fuel the #MeToo movement of women speaking out against sexual harassment and abuse by powerful men in media, politics and other industries.
