The haul consisted of seven gold, 15 silver and 10 bronze, and was boosted by John McGlashan College's dominance on the water.
McGlashan accounted for eight of Otago's medals - one gold, six silver and one bronze - a good sign before next month's Maadi Cup on Lake Ruataniwha.
It also followed a successful day at the Head of the Harbour regatta in Dunedin last weekend, when it retained the George Thorn Trophy.
McGlashan ended Otago Boys' High School's monopoly on the trophy, which is awarded for boys aggregate points during the regatta, last year when it ensured the trophy had a new home for the first time since 1969.
Wakatipu High School also had a successful weekend, winning six medals - one gold, two silver and three bronze.
Lucia King-Smith and Francesca Archibald snared the gold medal in the girls under-15 double sculls final, when they romped across the line in 8min 12.35sec, almost 6sec ahead of Meghan Templeton and Phoebe Trolove, of Craighead Diocesan School.
Alexander Byars and Jack McLaughlan accounted for McGlashan's lone gold medal. The pair cruised through their boys under-15 double sculls heat, before winning the final in convincing fashion.
They crossed the line in the medal race in 7min 41.39sec, well clear of Ethan Saywell and Alex Cartwright, of Shirley Boys' High School, who snared silver in 7min 47.71secByars and McLaughlan also won silver in the boys under-15 coxed quad, when they combined with Will Turne, Nic Chamberlain and coxswain Michael Beattie.
McLaughlan then jumped into the under-16 coxed quad with Josh Smith, Ben Macdonald, Max Gomez and coxswain Beattie to double his silver medal tally.
After finishing third in their heat, the crew pushed eventual winner Roncalli College to the brink in the final, but had to settle for silver a few seconds back in 7min 1.47sec.
Bradley Leydon and Alexander Timmings also had a good couple of days for the school.
The pair won silver in the boys under-17 double sculls, before joining Lochie Bain, Josh Smith and coxswain Oscar Cochrane to do the same in the boys under-17 coxed quadLeydon won a third silver medal on his own in the boys under-17 single.
He qualified for the final after winning his heat, but could not upstage Mark Taylor, of Waitaki Boys' High School, who was almost 6sec faster on his way to gold in 7min 50.20sec.
Lochie Chittock and Woody Kirkwood accounted for John McGlashan's other silver medal, in the boys under-18 double, while Macdonald and Gomez won bronze in the boys under-16 double.
St Hilda's Collegiate's girls under-15 coxed quad of Alannah Hamilton, Emma Burnside, Helen Knott, Emily Hurdle and coxswain Mia Knott won one of Otago's other gold medals.
The crew outgunned Ashburton College to win in 7min 58.36sec, while Dunstan High School's Erin Calder, Ella Creagh, Iona Morton, Aisha Born and coxswain Sophie Williamson won bronze.
But Calder, Creagh, Morton and Born did two better to win gold in the girls under-15 coxed octuple sculls with Shayla Alexander, Andre Schaap, Grace Ellis, Shaye Scott and coxswain Skye Morton.
Columba College's Sara Griffin, Heidi Wright, Sophie Anderson, Millie Wright and coxswain Margot Darling won gold in the girls under-18 lightweight coxed four, while Dunstan High School's Macaela Turfus and Sydney Cook won the girls under-18 lightweight double.
Turfus and Cook won in 7min 50.96sec to edge St Hilda's Lili Sabonadiere and Claudia Maker by 2.99sec.
