A Southland highway has reopened after a crash that left four people injured, one critically, on Monday.

A police spokeswoman said they were called to the two-vehicle crash, on State Highway 99/Stafford St between Dover St and Dudley St West in Orepuki, about 12.40pm. 

“One person received critical injuries, two people received moderate injuries and one person received minor injuries,” the spokeswoman said. 

The road was closed all afternoon and into the evening, to allow for a Serious Crash Unit investigation.

Just before 7pm, NZ Transport Agency Waka Kotahi advised it had reopened