A serious crash has closed State Highway 99/Stafford St in Orepuki, Southland. 

A police spokeswoman said they were called to the two-vehicle crash, between Dover St and Dudley St West, about 12.40pm. 

“One person received critical injuries, two people received moderate injuries and one person received minor injuries,” the spokeswoman said. 

The road is closed but a detour within Orepuki is available. 

Motorists are advised to expect delays.