A spokeswoman said police were alerted to the crash at the intersection of State Highway 6 and Kent St about 11.20am.
Two people were reportedly in the car but it was not clear how many people were on board the bus.
Fire and Emergency New Zealand crews were in attendance and one person was removed from the vehicle after becoming trapped.
There were no road blocks in place and no ''serious'' injuries had been reported ''at this stage''.
Police were also alerted to a collision between a patrol vehicle and a car at the intersection of SH6 and McBride St in Frankton about 11.30am.
The patrol car was responding to another crash in Queenstown when the crash occurred.
No injuries were reported and there was some ''minor'' damage to both vehicles.