The side is still right in the mix for the playoffs, sitting seventh on the ladder with four games left to play.
The Highlanders play the Blues and the Crusaders, both away, before a three-week break for the June internationals.
This will be the first time teams in the Super 15 will have had to accommodate the break in their season.
Last year, the first season of the expanded Super 15, no internationals were played in June because of the World Cup.
The Highlanders will play the Crusaders in Christchurch on June 1 and their next game will be against the Chiefs at Forsyth Barr Stadium on June 29.
Highlanders coach Jamie Joseph said the side would break up for a week after the Crusaders game and would then come back for the next two weeks to train and get ready to take on the Chiefs.
"Some guys need a bit of a rest and a break while others may need a bit of rehab on their bodies. Others may look at playing a bit of club footy," Joseph said.
"But we've had quite a big year and we have had the hardest run of any team in terms of playing continuous games so we need to have a break."
There had been a suggestion the team would play a game during the three-week break, which other teams were doing, but with many of its players likely to be involved in the match between North and South in Dunedin, Joseph said there was no need to play a game.
It was better to get players right and rehab injuries than play a match.
The Highlanders will come back and play two games, against the Chiefs and the Reds, before having the bye in the final round.
Joseph said the bye in the last round, with four points guaranteed, was great if the team was in the playoffs, as it would give it a week off to rest up and get ready for the finals.
The players had recovered well from the close victory over the Bulls on Saturday night, and had started preparations for the Blues in Auckland on Saturday night.
The Blues are having a well documented poor season, but Joseph said he was not worried about them, and was simply concentrating on getting his own side prepared for the game at Eden Park.
