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A police spokeswoman said a ute ran into the Dunedin Carpet Flooring Xtra building in Stone St shortly before 1pm.
The business adjoins Fusion Plastics and the ute went through a window. A Carpet Flooring Xtra staff member said no-one there saw the crash happen.
"We just heard the bang. It shook the building."
She and other staff investigated the noise.
"I kind of just thought ‘oh heck’ and went and saw the person."
A St John spokesman said ambulance services were alerted to the incident at 12.45pm and arrived at 12.54pm.
A person with moderate injuries was transported to Dunedin Hospital.
A Fire and Emergency New Zealand spokesman said it attended to assist with traffic control.
No-one was trapped in the vehicle or the building.
It was unclear what caused the incident.