Emergency services at the scene of the crash. Photo by Rhys Chamberlain
A witness believed two people were getting into a VW Beetle when a Toyota Vitz rounded a corner, lost control and hit a parked car.
He said two people were in the car travelling down the hill, one of which escaped uninjured.
A second witness said the car hit two people getting into a parked car.
Firefighters and ambulance staff attended and police cordoned off the area about 4.30pm.
A St John spokeswoman said three ambulances attended and patients were taken to the emergency department.
Police issued a statement after 5.30pm saying a serious crash investigator would attend the scene and Brockville Rd was closed with detours in place.