Dr Mapp holds the safe National seat of North Shore and has been in Parliament since 1996.
He was appointed Minister of Defence and Minister of Research, Science and Technology after National won the 2008 election.
"I will have been a Member of Parliament for 15 years and have always endeavoured to be an effective member for the North Shore electorate,'' Dr Mapp said.
"When the election is held I will also have completed three years in Cabinet.''
Dr Mapp said he believed he had set a ``strategic direction'' in his portfolios which would be enduring.
"The Defence White Paper outlines New zealand's strategic setting, capabilities and funding to provide a clear pathway forward,'' he said.
"Science and innovation are central to the Government's economic agenda. The changes over the last two years are intended to achieve real gains in economic growth.''
Dr Mapp said he would be busy next year cementing in the changes.
"North Shore will be selecting a new candidate for the 2011 election. I look forward to supporting that person in the campaign,'' he said.