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The Rees Hotel has gained three nominations and the Hilton two, while Millbrook Resort and Fiordland Lodge have also gained nominations in some categories.
The awards are now in their 10th year and attracted a record 2300 entries across 41 categories from Australia, New Zealand and the South Pacific.
The Rees Hotel and the Hilton both received nominations for the New Zealand hotel of the year award, while the Hilton and Arrowtown's Millbrook will go head to head in the bid for the New Zealand regional property award.
The Southern Lakes region was heavily represented in the lodge category, Glenorchy's Blanket Bay, Te Anau's Fiordland Lodge and Queenstown's Matakauri Lodge all gaining nominations.
Fiordland Lodge also received a service to the community nomination and one for the environmental programme award.
Individual award nominations were for Tanya Dennis, of Sofitel Queenstown, and Andy Cunningham, of Fiordland Lodge.
The Rees Hotel chief executive Mark Rose and executive chef Ben Batterbury have reached the final cut for the best New Zealand general manager award and the best hotel chef award respectively.
All qualifying candidates were required to submit a written entry and underwent a selection process conducted by 50 industry leaders, travel writers, experts and key clients.
Mr Rose praised his team for their consistent efforts and put his own nomination down to a "collective and outstanding effort by those around him".
"It's very satisfying for the hotel to be recognised by its peers for the second year in a row."
The Rees has been nominated for two out of the three years it has been open.